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Dr. Kacir's ADHD Blog

Methylphenidate in Adults

Eighteen studies of methylphenidate, the active ingredient in Ritalin, Concerta and Metadate, were reviewed to explore its role in treating adults with ADHD.  From these studies, methylphenidate had a "moderate" effect on ADHD symptoms that increased with increasing doses.  The average dose in adults was about 60 mg per day.  The reviewers were unable to determine if there was a difference in effect for different forms of the medicine.  (For example, long acting vs short-acting.)  Those patients who had problems with substance use did not respond as well as those without substance use disorders.  My experience in using methylphenidate in adults with ADHD is consistent with these findings -- I find that Concerta and generic methylphenidate are both effective and that the main differences are in the side effects and the length of action rather than in how effective they are.
 

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