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Dr. Kacir's ADHD Blog

New evidence of ADHD genetics

I just read a report on an article in The Lancet, a British medical journal.  It documents a study comparing the genes of about 400 children with ADHD to those of more than a thousand kids without symptoms of ADHD.  They found that genes from those with ADHD were twice as likely to have extra copies or fewer copies of certain genes associated with brain function.  This is the first direct genetic evidence for ADHD and defines it as a neurodevelopmental condition and NOT a behavior disorder!

29 Comments to New evidence of ADHD genetics:

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Heather Mouser on Friday, October 08, 2010 3:34 PM
Will the Micro Array scan tell you this info? How do you present this to the school where they will understand? What do you do when "sensory issues" won't allow child to tolerate stimulants? I just want to know for sure, ADHD is the only DX that we need to treat. It seems so much deeper than that.
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Dr. Kacir on Friday, October 08, 2010 4:03 PM
Copy number variability, on which this study is based, is useful primarily in research, where hundreds of genomes from one defined population are compared to those of another population. It is not useful in the diagnosis of any individual person.
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They found that genes from those with ADHD were twice as likely to have extra copies.
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I think information like this should be strictly restricted to academic platforms as people need to educate themselves before anything else and learn more than just tidbits of information.
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